使用本网站需要启用 JavaScript, 请启用后刷新页面获得更好的体验
登录
注册
首页
个人居家检测
临床应用研究
科研合作项目
合作与服务
社区
纯合片段分析
姓氏祖源
祖源平均脸
基因关系
基因保险助手
原始数据
使用 WeGene 需要启用 Cookies, 请启用后刷新页面获得更好的体验
社区首页
小组
饮食对肥胖的影响
饮食对肥胖的影响
发起讨论
饮食对肥胖的影响
1 个讨论
只看精华帖
按热门排序
按最新排序
对体重有影响的药物——丁香园公众号，作者肖丹华
chengang
• 最后回复
aningspring
•
2015-06-02 16:15
2062
1
• 来自相关小组
发起讨论
饮食对肥胖的影响
1 个讨论
相关基因
PPARG
位点：RS1801282
APOA2
位点：RS5082
APOA5
位点：RS662799
Montagnana M, et al. The Pro12Ala polymorphism of the PPARG gene is not associated with the metabolic syndrome in an urban population of middle-aged Swedish individuals. 2008
Wellcome Trust Case Control Consortium, et al. Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. 2007
Johnson W, et al. PPARG Pro12Ala genotype and risk of cognitive decline in elders? Maybe with diabetes. 2008
Regieli JJ, et al. PPAR gamma variant influences angiographic outcome and 10-year cardiovascular risk in male symptomatic coronary artery disease patients. 2009
Diabetes Genetics Initiative of Broad Institute of Harvard and MIT, Lund University, and Novartis Institutes of BioMedical Research, et al. Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels. 2007
Scott LJ, et al. A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants. 2007
Zeggini E, et al. Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes. 2007
Thorsby PM, et al. Comparison of genetic risk in three candidate genes (TCF7L2, PPARG, KCNJ11) with traditional risk factors for type 2 diabetes in a population-based study--the HUNT study. 2015
Habalová V, et al. Rapid and cost effective genotyping method for polymorphisms in PPARG, PPARGC1 and TCF7L2 genes. 2009
Matsuo T, et al. PPARG genotype accounts for part of individual variation in body weight reduction in response to calorie restriction. 2009
Yue H, et al. No association between polymorphisms of peroxisome [corrected] proliferator-activated receptor-gamma gene and peak bone mineral density variation in Chinese nuclear families. 2010
De Cosmo S, et al. Impact of the PPAR-gamma2 Pro12Ala polymorphism and ACE inhibitor therapy on new-onset microalbuminuria in type 2 diabetes: evidence from BENEDICT. 2009
Ben Ali S, et al. Gender-specific effect of Pro12Ala polymorphism in peroxisome proliferator-activated receptor gamma-2 gene on obesity risk and leptin levels in a Tunisian population. 2009
Tellechea ML, et al. Pro12Ala polymorphism of the peroxisome proliferatoractivated receptor-gamma gene is associated with metabolic syndrome and surrogate measures of insulin resistance in healthy men: interaction with smoking status. 2009
Ruchat SM, et al. Improvements in glucose homeostasis in response to regular exercise are influenced by the PPARG Pro12Ala variant: results from the HERITAGE Family Study. 2010
Gouda HN, et al. The association between the peroxisome proliferator-activated receptor-gamma2 (PPARG2) Pro12Ala gene variant and type 2 diabetes mellitus: a HuGE review and meta-analysis. 2010
Xu W, et al. PPARgamma polymorphisms and cancer risk: a meta-analysis involving 32,138 subjects. 2010
Fisher E, et al. A two-step association study identifies CAV2 rs2270188 single nucleotide polymorphism interaction with fat intake in type 2 diabetes risk. 2011
Bego T, et al. Association of PPARG and LPIN1 gene polymorphisms with metabolic syndrome and type 2 diabetes. 2011
Namvaran F, et al. Polymorphism of peroxisome proliferator-activated receptor γ (PPARγ) Pro12Ala in the Iranian population: relation with insulin resistance and response to treatment with pioglitazone in type 2 diabetes. 2011
Namvaran F, et al. Genotyping of peroxisome proliferator-activated receptor gamma (PPAR-γ) polymorphism (Pro12Ala) in Iranian population. 2011
Sainz J, et al. Effect of type 2 diabetes predisposing genetic variants on colorectal cancer risk. 2012
Guo WL, et al. [Meta-analysis of the association of Pro12Ala polymorphism of peroxisome proliferator activated receptor gamma gene with type 2 diabetes in Chinese Han population]. 2011
Ho JS, et al. Association of the PPARG Pro12Ala polymorphism with type 2 diabetes and incident coronary heart disease in a Hong Kong Chinese population. 2012
Kurzawski M, et al. Analysis of common type 2 diabetes mellitus genetic risk factors in new-onset diabetes after transplantation in kidney transplant patients medicated with tacrolimus. 2012
Mössner R, et al. Variations in the peroxisome proliferator-activated receptor-gamma gene and melanoma risk. 2007
Chen L, et al. Effect of the peroxisome proliferators-activated receptor (PPAR) gamma 3 gene on BMI in 1,210 school students from Morelos, Mexico. 2015
Nitz I, et al. Analysis of PGC-1alpha variants Gly482Ser and Thr612Met concerning their PPARgamma2-coactivation function. 2007
Florez JC, et al. Effects of the type 2 diabetes-associated PPARG P12A polymorphism on progression to diabetes and response to troglitazone. 2007
Wang Y, et al. Nested case-control study of energy regulation candidate gene single nucleotide polymorphisms and breast cancer. 2007
Huang HY, et al. Frequencies of single nucleotide polymorphisms in genes regulating inflammatory responses in a community-based population. 2007
Lyssenko V, et al. Genetic prediction of future type 2 diabetes. 2005
Ioannidis JP, et al. Heterogeneity in meta-analyses of genome-wide association investigations. 2007
Nemoto M, et al. Genetic association of glutathione peroxidase-1 with coronary artery calcification in type 2 diabetes: a case control study with multi-slice computed tomography. 2007
Cupples LA, et al. The Framingham Heart Study 100K SNP genome-wide association study resource: overview of 17 phenotype working group reports. 1948
Meigs JB, et al. Genome-wide association with diabetes-related traits in the Framingham Heart Study. 2007
Fox CS, et al. Genome-wide association to body mass index and waist circumference: the Framingham Heart Study 100K project. 2007
Kilpeläinen TO, et al. SNPs in PPARG associate with type 2 diabetes and interact with physical activity. 2008
Rhee EJ, et al. The association of Pro12Ala polymorphism of peroxisome proliferator-activated receptor-gamma gene with serum osteoprotegerin levels in healthy Korean women. 2007
Omori S, et al. Association of CDKAL1, IGF2BP2, CDKN2A/B, HHEX, SLC30A8, and KCNJ11 with susceptibility to type 2 diabetes in a Japanese population. 2008
Brockmöller J, et al. Pharmacogenetics: data, concepts and tools to improve drug discovery and drug treatment. 2008
Hancock AM, et al. Adaptations to climate in candidate genes for common metabolic disorders. 2008
Gallicchio L, et al. Genetic polymorphisms of peroxisome proliferator-activated receptors and the risk of cardiovascular morbidity and mortality in a community-based cohort in washington county, Maryland. 1989
Haworth CM, et al. No evidence for association between BMI and 10 candidate genes at ages 4, 7 and 10 in a large UK sample of twins. 2008
Lu Q, et al. Using the optimal receiver operating characteristic curve to design a predictive genetic test, exemplified with type 2 diabetes. 2008
Mar-Heyming R, et al. Association of stearoyl-CoA desaturase 1 activity with familial combined hyperlipidemia. 2008
Zeggini E, et al. Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes. 2008
Cresci S, et al. PPAR Genomics and Pharmacogenomics: Implications for Cardiovascular Disease. 2015
Qu HQ, et al. Association analysis of type 2 diabetes Loci in type 1 diabetes. 2008
Marvelle AF, et al. Association of FTO with obesity-related traits in the Cebu Longitudinal Health and Nutrition Survey (CLHNS) Cohort. 2008
Cauchi S, et al. The genetic susceptibility to type 2 diabetes may be modulated by obesity status: implications for association studies. 2008
Penco S, et al. New application of intelligent agents in sporadic amyotrophic lateral sclerosis identifies unexpected specific genetic background. 2008
Myles S, et al. Worldwide population differentiation at disease-associated SNPs. 2008
Lango H, et al. Assessing the combined impact of 18 common genetic variants of modest effect sizes on type 2 diabetes risk. 2008
Sanghera DK, et al. Impact of nine common type 2 diabetes risk polymorphisms in Asian Indian Sikhs: PPARG2 (Pro12Ala), IGF2BP2, TCF7L2 and FTO variants confer a significant risk. 2008
Simoni M, et al. Functional genetic polymorphisms and female reproductive disorders: Part I: Polycystic ovary syndrome and ovarian response. 2008
Gaulton KJ, et al. Comprehensive association study of type 2 diabetes and related quantitative traits with 222 candidate genes. 2008
Slatkin M, et al. Exchangeable models of complex inherited diseases. 2008
van Hoek M, et al. Predicting type 2 diabetes based on polymorphisms from genome-wide association studies: a population-based study. 2008
Ackert-Bicknell CL, et al. PPARG by dietary fat interaction influences bone mass in mice and humans. 2008
Florez JC, et al. Clinical review: the genetics of type 2 diabetes: a realistic appraisal in 2008. 2008
Tranah GJ, et al. Genetic variation in candidate osteoporosis genes, bone mineral density, and fracture risk: the study of osteoporotic fractures. 2008
Tempfer CB, et al. Functional genetic polymorphisms and female reproductive disorders: part II--endometriosis. 2009
Smith CE, et al. Perilipin polymorphism interacts with dietary carbohydrates to modulate anthropometric traits in hispanics of Caribbean origin. 2008
Mohlke KL, et al. Metabolic and cardiovascular traits: an abundance of recently identified common genetic variants. 2008
Chang MH, et al. Prevalence in the United States of selected candidate gene variants: Third National Health and Nutrition Examination Survey, 1991-1994. 2009
Küry S, et al. Low-penetrance alleles predisposing to sporadic colorectal cancers: a French case-controlled genetic association study. 2008
Slattery ML, et al. Colon tumor mutations and epigenetic changes associated with genetic polymorphism: insight into disease pathways. 2009
Cho YM, et al. Type 2 diabetes-associated genetic variants discovered in the recent genome-wide association studies are related to gestational diabetes mellitus in the Korean population. 2009
Meigs JB, et al. Genotype score in addition to common risk factors for prediction of type 2 diabetes. 2008
Timpson NJ, et al. Adiposity-related heterogeneity in patterns of type 2 diabetes susceptibility observed in genome-wide association data. 2009
Paré G, et al. Novel association of HK1 with glycated hemoglobin in a non-diabetic population: a genome-wide evaluation of 14,618 participants in the Women's Genome Health Study. 2008
Wang X, et al. A meta-analysis of candidate gene polymorphisms and ischemic stroke in 6 study populations: association of lymphotoxin-alpha in nonhypertensive patients. 2009
Johnson AD, et al. An open access database of genome-wide association results. 2009
Osawa H, et al. PPARgamma Pro12Ala Pro/Pro and resistin SNP-420 G/G genotypes are synergistically associated with plasma resistin in the Japanese general population. 2009
Zeggini E, et al. Meta-analysis in genome-wide association studies. 2009
Wieczorek S, et al. Genetic variability of RXRB, PPARA, and PPARG in Wegener's granulomatosis. 2009
Zee RY, et al. Genetic risk factors in recurrent venous thromboembolism: A multilocus, population-based, prospective approach. 2009
Qi L, et al. Genetic predisposition, Western dietary pattern, and the risk of type 2 diabetes in men. 2009
McCarthy MI, et al. Genome-wide association studies in type 2 diabetes. 2009
Brito EC, et al. Previously associated type 2 diabetes variants may interact with physical activity to modify the risk of impaired glucose regulation and type 2 diabetes: a study of 16,003 Swedish adults. 2009
Janssens AC, et al. Genome-based prediction of common diseases: methodological considerations for future research. 2009
Deeb SS, et al. The role of the PGC1α Gly482Ser polymorphism in weight gain due to intensive diabetes therapy. 2009
Takeuchi F, et al. Confirmation of multiple risk Loci and genetic impacts by a genome-wide association study of type 2 diabetes in the Japanese population. 2009
Raj SM, et al. No association of multiple type 2 diabetes loci with type 1 diabetes. 2009
Grant RW, et al. Genetic architecture of type 2 diabetes: recent progress and clinical implications. 2009
Stancáková A, et al. Association of 18 confirmed susceptibility loci for type 2 diabetes with indices of insulin release, proinsulin conversion, and insulin sensitivity in 5,327 nondiabetic Finnish men. 2009
Southam L, et al. Is the thrifty genotype hypothesis supported by evidence based on confirmed type 2 diabetes- and obesity-susceptibility variants? 2009
Breyer JP, et al. Genetic variants and prostate cancer risk: candidate replication and exploration of viral restriction genes. 2009
Abhary S, et al. A systematic meta-analysis of genetic association studies for diabetic retinopathy. 2009
Salanti G, et al. Underlying genetic models of inheritance in established type 2 diabetes associations. 2009
Dong LM, et al. An analysis of growth, differentiation and apoptosis genes with risk of renal cancer. 2009
Dedoussis GV, et al. Peroxisome proliferator-activated receptor-gamma (PPARgamma) Pro12Ala polymorphism and risk for pediatric obesity. 2015
Combarros O, et al. APOE dependent-association of PPAR-γ genetic variants with Alzheimer's disease risk. 2011
Sanghera DK, et al. PPARG and ADIPOQ gene polymorphisms increase type 2 diabetes mellitus risk in Asian Indian Sikhs: Pro12Ala still remains as the strongest predictor. 2010
Hu C, et al. PPARG, KCNJ11, CDKAL1, CDKN2A-CDKN2B, IDE-KIF11-HHEX, IGF2BP2 and SLC30A8 are associated with type 2 diabetes in a Chinese population. 2009
Browning BL, et al. Simultaneous genotype calling and haplotype phasing improves genotype accuracy and reduces false-positive associations for genome-wide association studies. 2009
Pawitan Y, et al. How many genetic variants remain to be discovered? 2009
Fradin DD, et al. Influence of control selection in genome-wide association studies: the example of diabetes in the Framingham Heart Study. 2009
Lu Q, et al. The effect of multiple genetic variants in predicting the risk of type 2 diabetes. 2009
An P, et al. Epistatic interactions of CDKN2B-TCF7L2 for risk of type 2 diabetes and of CDKN2B-JAZF1 for triglyceride/high-density lipoprotein ratio longitudinal change: evidence from the Framingham Heart Study. 2009
Parikh H, et al. Prioritizing genes for follow-up from genome wide association studies using information on gene expression in tissues relevant for type 2 diabetes mellitus. 2009
Pecioska S, et al. Association between type 2 diabetes loci and measures of fatness. 2010
Talmud PJ, et al. Utility of genetic and non-genetic risk factors in prediction of type 2 diabetes: Whitehall II prospective cohort study. 2010
Wang F, et al. Effect of genetic variants in KCNJ11, ABCC8, PPARG and HNF4A loci on the susceptibility of type 2 diabetes in Chinese Han population. 2009
Lott L, et al. A genomics study of type 2 diabetes mellitus in U.S. Air Force personnel. 2009
Wen J, et al. Investigation of type 2 diabetes risk alleles support CDKN2A/B, CDKAL1, and TCF7L2 as susceptibility genes in a Han Chinese cohort. 2010
Chauhan G, et al. Impact of common variants of PPARG, KCNJ11, TCF7L2, SLC30A8, HHEX, CDKN2A, IGF2BP2, and CDKAL1 on the risk of type 2 diabetes in 5,164 Indians. 2010
Hawken SJ, et al. The utility and predictive value of combinations of low penetrance genes for screening and risk prediction of colorectal cancer. 2010
Dedoussis GV, et al. An age-dependent diet-modified effect of the PPARγ Pro12Ala polymorphism in children. 2011
Morgan AR, et al. Obesity and diabetes genes are associated with being born small for gestational age: results from the Auckland Birthweight Collaborative study. 2010
Hildebrandt MA, et al. Genetic variants in inflammation-related genes are associated with radiation-induced toxicity following treatment for non-small cell lung cancer. 2010
Estivalet AA, et al. D2 Thr92Ala and PPARγ2 Pro12Ala polymorphisms interact in the modulation of insulin resistance in type 2 diabetic patients. 2011
Folwaczny M, et al. Variants of the human PPARG locus and the susceptibility to chronic periodontitis. 2011
Mihaescu R, et al. Genetic risk profiling for prediction of type 2 diabetes. 2011
Sousa AG, et al. Genetic variants of diabetes risk and incident cardiovascular events in chronic coronary artery disease. 2011
Bouchard-Mercier A, et al. Effects of peroxisome proliferator-activated receptors, dietary fat intakes and gene-diet interactions on peak particle diameters of low-density lipoproteins. 2011
Poliska S, et al. Association of peroxisome proliferator-activated receptor gamma polymorphisms with inflammatory bowel disease in a Hungarian cohort. 2012
Dragojevič J, et al. PPARG gene promoter polymorphism is associated with non-traumatic hip fracture risk in the elderly Slovenian population: a pilot study. 2011
Martínez-Gómez LE, et al. A replication study of the IRS1, CAPN10, TCF7L2, and PPARG gene polymorphisms associated with type 2 diabetes in two different populations of Mexico. 2011
Shi H, et al. Application of back propagation artificial neural network on genetic variants in adiponectin ADIPOQ, peroxisome proliferator-activated receptor-γ, and retinoid X receptor-α genes and type 2 diabetes risk in a Chinese Han population. 2012
Delahanty LM, et al. Genetic predictors of weight loss and weight regain after intensive lifestyle modification, metformin treatment, or standard care in the Diabetes Prevention Program. 2012
Hotta K, et al. Association between type 2 diabetes genetic susceptibility loci and visceral and subcutaneous fat area as determined by computed tomography. 2012
Park SE, et al. Impact of common type 2 diabetes risk gene variants on future type 2 diabetes in the non-diabetic population in Korea. 2012
Alsaleh A, et al. PPARγ2 gene Pro12Ala and PPARα gene Leu162Val single nucleotide polymorphisms interact with dietary intake of fat in determination of plasma lipid concentrations. 2012
Prakash J, et al. Association of PPAR-γ gene polymorphisms with obesity and obesity-associated phenotypes in North Indian population. 2012
Galbete C, et al. Lifestyle factors modify obesity risk linked to PPARG2 and FTO variants in an elderly population: a cross-sectional analysis in the SUN Project. 2013
Manning AK, et al. A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance. 2012
Raza ST, et al. Association of MTHFR and PPARγ2 gene polymorphisms in relation to type 2 diabetes mellitus cases among north Indian population. 2012
Chan KH, et al. Common genetic variants in peroxisome proliferator-activated receptor-γ (PPARG) and type 2 diabetes risk among Women's Health Initiative postmenopausal women. 2013
Sahebkar A, et al. Does PPARγ2 gene Pro12Ala polymorphism affect nonalcoholic fatty liver disease risk? Evidence from a meta-analysis. 2013
Tariq K, et al. Association of Pro12Ala polymorphism in peroxisome proliferator activated receptor gamma with proliferative diabetic retinopathy. 2013
Jalil SF, et al. Association of Pro12Ala (rs1801282) variant of PPAR gamma with rheumatoid arthritis in a Pakistani population. 2014
Mtiraoui N, et al. Contribution of common variants of ENPP1, IGF2BP2, KCNJ11, MLXIPL, PPARγ, SLC30A8 and TCF7L2 to the risk of type 2 diabetes in Lebanese and Tunisian Arabs. 2012
Shibata N, et al. Lack of Genetic Associations of PPAR-γ and PGC-1α with Alzheimer's Disease and Parkinson's Disease with Dementia. 2013
Carlos FF, et al. Association of FTO and PPARG polymorphisms with obesity in Portuguese women. 2013
Jeon C, et al. Genetic variants of peroxisome proliferator-activated receptor δ are associated with gastric cancer. 2013
Estrada-Velasco BI, et al. IRS1, TCF7L2, ADRB1, PPARG, and HHEX polymorphisms associated with atherogenic risk in Mexican population. 2013
Chen C, et al. Association between six genetic polymorphisms and colorectal cancer: a meta-analysis. 2014
Kommoju UJ, et al. Association of IRS1, CAPN10, and PPARG gene polymorphisms with type 2 diabetes mellitus in the high-risk population of Hyderabad, India. 2014
Barth SW, et al. Moderate effects of apple juice consumption on obesity-related markers in obese men: impact of diet-gene interaction on body fat content. 2012
Kim KZ, et al. Polymorphisms in adiposity-related genes are associated with age at menarche and menopause in breast cancer patients and healthy women. 2012
Wang Y, et al. Quantitative evaluation of common polymorphism (rs1801282) in the PPARγ2 gene and hypertension susceptibility. 2012
Ding S, et al. The meta-analysis of the association of PPARG P12A, C161T polymorphism and coronary heart disease. 2012
Wang C, et al. Quantitative assessment of the influence of PPARG P12A polymorphism on gestational diabetes mellitus risk. 2013
Pei Q, et al. PPAR-γ2 and PTPRD gene polymorphisms influence type 2 diabetes patients' response to pioglitazone in China. 2013
Trombetta M, et al. PPARG2 Pro12Ala and ADAMTS9 rs4607103 as "insulin resistance loci" and "insulin secretion loci" in Italian individuals. The GENFIEV study and the Verona Newly Diagnosed Type 2 Diabetes Study (VNDS) 4. 2013
Patel CJ, et al. Systematic identification of interaction effects between genome- and environment-wide associations in type 2 diabetes mellitus. 2013
Dayeh TA, et al. Identification of CpG-SNPs associated with type 2 diabetes and differential DNA methylation in human pancreatic islets. 2013
Bank S, et al. Polymorphisms in the inflammatory pathway genes TLR2, TLR4, TLR9, LY96, NFKBIA, NFKB1, TNFA, TNFRSF1A, IL6R, IL10, IL23R, PTPN22, and PPARG are associated with susceptibility of inflammatory bowel disease in a Danish cohort. 2014
Hsiao TJ, et al. The Pro12Ala polymorphism in the peroxisome proliferator-activated receptor gamma (PPARG) gene in relation to obesity and metabolic phenotypes in a Taiwanese population. 2015
Zhang Y, et al. The gene polymorphisms of UCP1 but not PPAR γ and TCF7L2 are associated with diabetic retinopathy in Chinese type 2 diabetes mellitus cases. 2015
DIAbetes Genetics Replication And Meta-analysis (DIAGRAM) Consortium, et al. Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. 2014
Wu Y, et al. Lack of genetic associations between PPAR-γ gene rs1801282 polymorphism and Alzheimer's disease in general population: a meta-analysis. 2015
Corella D, et al. The -256T>C polymorphism in the apolipoprotein A-II gene promoter is associated with body mass index and food intake in the genetics of lipid lowering drugs and diet network study. 2007
Xiao J, et al. The apolipoprotein AII rs5082 variant is associated with reduced risk of coronary artery disease in an Australian male population. 2008
Duesing K, et al. Evaluating the association of common APOA2 variants with type 2 diabetes. 2009
Delgado-Lista J, et al. An apolipoprotein A-II polymorphism (-265T/C, rs5082) regulates postprandial response to a saturated fat overload in healthy men. 2007
Haworth CM, et al. No evidence for association between BMI and 10 candidate genes at ages 4, 7 and 10 in a large UK sample of twins. 2008
Smith CE, et al. Apolipoprotein A2 polymorphism interacts with intakes of dairy foods to influence body weight in 2 U.S. populations. 2013
De Caterina R, et al. Strong association of the APOA5-1131T>C gene variant and early-onset acute myocardial infarction. 2011
Corella D, et al. APOA5 gene variation modulates the effects of dietary fat intake on body mass index and obesity risk in the Framingham Heart Study. 2007
Wang J, et al. Polygenic determinants of severe hypertriglyceridemia. 2008
Liu ZK, et al. Associations of polymorphisms in the apolipoprotein A1/C3/A4/A5 gene cluster with familial combined hyperlipidaemia in Hong Kong Chinese. 2010
Ken-Dror G, et al. Different effects of apolipoprotein A5 SNPs and haplotypes on triglyceride concentration in three ethnic origins. 2010
Ariza MJ, et al. Additive effects of LPL, APOA5 and APOE variant combinations on triglyceride levels and hypertriglyceridemia: results of the ICARIA genetic sub-study. 2010
Jiang CQ, et al. A single nucleotide polymorphism in APOA5 determines triglyceride levels in Hong Kong and Guangzhou Chinese. 2010
Horvatovich K, et al. Haplotype analysis of the apolipoprotein A5 gene in obese pediatric patients. 2011
De Caterina R, et al. Strong association of the APOA5-1131T>C gene variant and early-onset acute myocardial infarction. 2011
Hong CJ, et al. Impact of apolipoprotein A5 (APOA5) polymorphisms on serum triglyceride levels in schizophrenic patients under long-term atypical antipsychotic treatment. 2012
Ward KJ, et al. Allelic drop-out may occur with a primer binding site polymorphism for the commonly used RFLP assay for the -1131T>C polymorphism of the Apolipoprotein AV gene. 2006
Pare G, et al. Genetic analysis of 103 candidate genes for coronary artery disease and associated phenotypes in a founder population reveals a new association between endothelin-1 and high-density lipoprotein cholesterol. 2007
Kathiresan S, et al. A genome-wide association study for blood lipid phenotypes in the Framingham Heart Study. 2007
Liao YC, et al. Multiple genetic determinants of plasma lipid levels in Caribbean Hispanics. 2008
Serre D, et al. Correction of population stratification in large multi-ethnic association studies. 2008
Pullinger CR, et al. An apolipoprotein A-V gene SNP is associated with marked hypertriglyceridemia among Asian-American patients. 2008
Dallongeville J, et al. The APOA5 Trp19 allele is associated with metabolic syndrome via its association with plasma triglycerides. 2008
Webster RJ, et al. The association of common genetic variants in the APOA5, LPL and GCK genes with longitudinal changes in metabolic and cardiovascular traits. 2009
Boes E, et al. Genetic-epidemiological evidence on genes associated with HDL cholesterol levels: a systematic in-depth review. 2009
Perez-Martinez P, et al. Association between glucokinase regulatory protein (GCKR) and apolipoprotein A5 (APOA5) gene polymorphisms and triacylglycerol concentrations in fasting, postprandial, and fenofibrate-treated states. 2009
Liu Y, et al. Pharmacogenetic association of the APOA1/C3/A4/A5 gene cluster and lipid responses to fenofibrate: the genetics of lipid-lowering drugs and diet network study. 2009
Deo RC, et al. Genetic differences between the determinants of lipid profile phenotypes in African and European Americans: the Jackson Heart Study. 2009
Ferrucci L, et al. Common variation in the beta-carotene 15,15'-monooxygenase 1 gene affects circulating levels of carotenoids: a genome-wide association study. 2009
Lanktree MB, et al. Replication of genetic associations with plasma lipoprotein traits in a multiethnic sample. 2009
Murray A, et al. Common lipid-altering gene variants are associated with therapeutic intervention thresholds of lipid levels in older people. 2009
Hegele RA, et al. A polygenic basis for four classical Fredrickson hyperlipoproteinemia phenotypes that are characterized by hypertriglyceridemia. 2009
Jackson KG, et al. Introduction to the DISRUPT postprandial database: subjects, studies and methodologies. 2010
Kraja AT, et al. Fenofibrate and metabolic syndrome. 2010
Triglyceride Coronary Disease Genetics Consortium and Emerging Risk Factors Collaboration, et al. Triglyceride-mediated pathways and coronary disease: collaborative analysis of 101 studies. 2010
Saleheen D, et al. Genetic determinants of major blood lipids in Pakistanis compared with Europeans. 2010
Lu Y, et al. Exploring genetic determinants of plasma total cholesterol levels and their predictive value in a longitudinal study. 2010
Ong KL, et al. Association of a genetic variant in the apolipoprotein A5 gene with the metabolic syndrome in Chinese. 2011
Feitosa MF, et al. Association of gene variants with lipid levels in response to fenofibrate is influenced by metabolic syndrome status. 2011
Yin RX, et al. Interactions of the apolipoprotein A5 gene polymorphisms and alcohol consumption on serum lipid levels. 2011
Bhaskar S, et al. Association of PON1 and APOA5 gene polymorphisms in a cohort of Indian patients having coronary artery disease with and without type 2 diabetes. 2011
Liu SM, et al. Rapid genotyping of APOA5 -1131T>C polymorphism using high resolution melting analysis with unlabeled probes. 2012
Rafiq S, et al. Evaluation of seven common lipid associated loci in a large Indian sib pair study. 2012
Takeuchi F, et al. Association of genetic variants influencing lipid levels with coronary artery disease in Japanese individuals. 2012
Hishida A, et al. Associations of apolipoprotein A5 (APOA5), glucokinase (GCK) and glucokinase regulatory protein (GCKR) polymorphisms and lifestyle factors with the risk of dyslipidemia and dysglycemia in Japanese - a cross-sectional data from the J-MICC Study. 2012
Hiramatsu M, et al. Synergistic effects of genetic variants of APOA5 and BTN2A1 on dyslipidemia or metabolic syndrome. 2012
Yin RX, et al. Interactions between the apolipoprotein a1/c3/a5 haplotypes and alcohol consumption on serum lipid levels. 2013
Can Demirdöğen B, et al. Apolipoprotein A5 polymorphisms in Turkish population: association with serum lipid profile and risk of ischemic stroke. 2012
Hsu MC, et al. Central obesity in males affected by a dyslipidemia-associated genetic polymorphism on APOA1/C3/A4/A5 gene cluster. 2013
Iqbal R, et al. Genetic association of lipid metabolism related SNPs with myocardial infarction in the Pakistani population. 2014
Wu Y, et al. Genetic association with lipids in Filipinos: waist circumference modifies an APOA5 effect on triglyceride levels. 2013
Hubacek JA, et al. The association between APOA5 haplotypes and plasma lipids is not modified by energy or fat intake: the Czech HAPIEE study. 2014
Nakatochi M, et al. Identification of an interaction between VWF rs7965413 and platelet count as a novel risk marker for metabolic syndrome: an extensive search of candidate polymorphisms in a case-control study. 2015
深圳市市场监督管理局企业主体身份公示
|
粤ICP备15012185号-2
|
互联网药品信息服务资格证书:（粤）-非经营性-2023-0379
中文 
English
纯合片段分析
姓氏祖源
祖源平均脸
基因关系
基因保险助手
原始数据
