JAMA子刊新报道：线粒体单倍群 I, J, K, O-X, T, U , A和M的自闭症风险较高

JAMA Psychiatry的8月23日发表的研究成果：Of 1624 patients with autism included in this study, 1299 were boys (80%) and 325 were girls (20%). Families in the Autism Genetic Resource Exchange collection (933 families, encompassing 4041 individuals: 1624 patients with ASD and 2417 healthy parents and siblings) had been previously recruited in the United States with no restrictions on age, sex, race/ethnicity, or socioeconomic status. Relative to the most common European haplogroup HHV, European haplogroups I, J, K, O-X, T, and U were associated with increased risk of ASD, as were Asian and Native American haplogroups A and M, with odds ratios ranging from 1.55 (95% CI, 1.16-2.06) to 2.18 (95% CI, 1.59-3) (adjusted P < .04). Hence, mtDNA haplogroup variation is an important risk factor for ASD.
 
参考文献：http://jamanetwork.com/journals/jamapsychiatry/article-abstract/2649278
 
母系是B的表示没有压力啊